Can a wife be forced to testify against her husband?
Not about any incidents that took place during the marriage or anything that was told to the spouse during the marriage. A wife may testify if she chooses, but nobody can force her to. That is called "spousal privilege" and it is essentially the same as the better-known attorney client privilege or doctor patient privilege.
That's a very short answer. Like any other privilege, there may be some situations where the privilege would not apply, but that is fact intensive. You should talk to a lawyer directly about your specific situation and get some tailored advice about your situation.